My system has 3x Graphics Cards, a 2080ti and two 5090's, I am using the 580.97 Driver, I have a high end system and if I run H22 with the 2080ti then H22 will constantly crash, but if I use one of the 5090 cards as the monitor outputs then H22 is stable and runs as expected, so there is an issue with running H22 with a RTX 2080ti, just thought I would relay my experience.

Just tried the daily build 22.0.423 with the 2080ti as the display and all seems to be good, no crashes... yet

Speak too soon, after a bit of editing... crash, so back to the 5090...